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Insulin Signaling Pathway

PAG Title Insulin Signaling Pathway
PAG ID WIG000361
Type P
Source Link MSigDB
Publication Reference NA
PAG Description The appropriate signaling through the insulin pathway is critical for the regulation of glucose levels and the avoidance of diabetes. Insulin forms a complex with the Insulin Receptor (IR) and b chains to form the active signaling complex. Through recruitment of adaptor molecules and the activation of RAS, the activated IR can cause transcriptional activation.
Species Homo sapiens
Quality Metric Scores nCoCo Score: 3,976
Information Content Rich
Other IDs M765
Base PAG ID WIG000361
Human Phenotyte Annotation
Curator PAGER curation team
Curator Contact PAGER-contact@googlegroups.com
Gene ID Gene symbol Gene name RP_score
Gene A Gene B Source SCORE

Gene A Gene B Mechanism Source
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