Insulin Signaling Pathway
PAG Title | Insulin Signaling Pathway |
PAG ID | WIG000361 |
Type | P |
Source Link | MSigDB |
Publication Reference | NA |
PAG Description | The appropriate signaling through the insulin pathway is critical for the regulation of glucose levels and the avoidance of diabetes. Insulin forms a complex with the Insulin Receptor (IR) and b chains to form the active signaling complex. Through recruitment of adaptor molecules and the activation of RAS, the activated IR can cause transcriptional activation. |
Species | Homo sapiens |
Quality Metric Scores | nCoCo Score: 3,976 |
Information Content | Rich |
Other IDs | M765 |
Base PAG ID | WIG000361 |
Human Phenotyte Annotation | |
Curator | PAGER curation team |
Curator Contact | PAGER-contact@googlegroups.com |
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